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Overactivated M1 macrophages exacerbate inflammation through secreting pro-inflammatory cytokines, driving joint damage, whereas immunosuppressive M2 macrophages are diminished, disrupting immune equilibrium (130)

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Bergandi L, Giuggia B, Alovisi M, Comba A, Silvagno F, Maule M, Aldieri E, Scotti N, Scacciatella P, Conrotto F, Berutti E, Pasqualini D (2019) Endothelial dysfunction marker variation in young adults with chronic apical periodontitis before and after endodontic treatment

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