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doi: 10.1016/j.immuni.2015.09.007 63 IshikawaTNanjoF

The mechanism of action also produces modest weight loss through calorie elimination (approximately 200 to 300 calories daily)

The term de-prescribing is used frequently in the weight loss industry, so it is important to clarify what it means

Pre-diabetes and metabolic syndrome are growing health concerns that affect millions of people

Results Significant placebo-adjusted decreases from baseline in blood pressure, low-density lipoprotein (LDL) cholesterol, triglycerides, ApoB, ApoC3, and hsCRP were observed following orforglipron treatment in participants with T2D and/or overweight or obesity

Hong et al., 2010