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Combining semaglutide with hormone therapy Understanding how semaglutide and hormone therapy work together explains why this dual approach offers a more effective, personalized weight management plan

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The 5-year risk of CKD was about 7% with SGLT2 inhibitors versus just over 8% with GLP-1s, suggesting a slight edge for SGLT2 inhibitors on pure kidney outcomes

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But it does require physician monitoring and is contraindicated in certain conditions including active cancer

However, it can cause gastrointestinal side effects including steatorrhoea (fatty stools)