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Jarrahi A, Braun M, Ahluwalia M, Gupta RV, Wilson M, Munie S, et al

By acting as a substrate for 3-mercaptopyruvate, NAC increases mitochondrial H 2 S levels, which can persulfonate cysteine residues on Keap1, impairing its ability to sequester Nrf2 in the cytosol

The Phase 2 data showed weight loss curves that had not plateaued, meaning longer treatment durations could push the numbers even higher

Furthermore, because of the possibility of adverse effects on a nursing infant, this therapy is generally avoided in women who are breastfeeding

Nalbantoglu, J

Shed providers can adjust the schedule based on tolerability, which is one advantage of having a dedicated medical team rather than a one-size-fits-all algorithm