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Mediation analysis was performed to probe the role of serum alkaline phosphatase (ALP) in the aforementioned relationship, and the network pharmacology analysis was also conducted to determine the potential pathways and key targets for vitamin B2 regulating bone health

In recent years, studies on SZ bodily fluids have consistently reported increased numbers of TLR4-positive monocytes and elevated TLR4 expression in the peripheral blood of schizophrenia patients (149, 153155), suggesting that TLR4 upregulation is a key factor in the immunopathological process of schizophrenia

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