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Oral contraceptives should be taken at least 1 hour before these medications or 4 hours after

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40 Perhaps most notably, recurrent vomiting, diarrhea, constipation, dysmotility, and pseudo-obstruction, as well as pancreatitis, may occur in the context of mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS)

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Reson Med 63 , 13571365 (2010)