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These findings uncover a non-canonical mechanism of action for GLP-1 analogs, highlighting a specific microbiota-endocannabinoid metabolic pathway as a potential therapeutic target for depression.

Alisa Hrustic is a health writer and editor

Understanding this bias is the secret to choosing the right tool for your specific goals

P values indicated, determined by two-tailed t -test ( a ) or one-way ANOVA with Dunnetts multiple comparisons test against CTRL ( b )

And studies done specifically with women in perimenopause or post-menopause show that tirzpeatide support weight loss and better body composition (smaller waist circumference, which indicates healthier visceral fat levels)

They work by mimicking the actions of the GLP-1 hormone, which regulates appetite and food intake