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Treatment Duloxetine Recommendations from the American Society of Clinical Oncology (ASCO) and from the European Society for Medical Oncology (ESMO) both include the antidepressant duloxetine (Cymbalta) as a moderate recommendation in patients with established, painful CIPN
The study was led by Bradley Peterson, MD, of the Keck School of Medicine of the University of Southern California and co-authors included Corinna Koebnick, PhD, and Brian S
The 40 mg/mL concentration is typically reserved for patients on higher maintenance doses, and it requires extremely careful measurement
Summary of Critical Appraisal The included study 13 achieved randomization using an interactive web response system, limiting the possibility that randomization was inadequate
Cloudiness or visible particles may indicate incomplete dissolution or contamination
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