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Tirzepatide represents a dual-action GLP-1 and GIP receptor agonist that requires careful dose escalation to achieve optimal results

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That reduces total caloric intake significantly, and a large, sustained deficit is a well-established driver of lean tissue loss regardless of what created it

For example, reactive microglia phagocyte pathogens and cellular debris, reactive astrocytes limit damage by erecting barriers to spread of inflammation and, together with the oligodendroglial lineage cells responsible for remyelinating axons, support postlesional regeneration

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