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Giorda CB, Sacerdote C, Nada E, Marafetti L, Baldi I, Gnavi R (2015) Incretin-based therapies and acute pancreatitis risk: a systematic review and meta-analysis of observational studies

Semaglutide and the Modern Era of GLP-1 Therapy Semaglutide, developed by Novo Nordisk, entered the market in 2017 and quickly became the dominant GLP-1 treatment option

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After the run-in period, patients with inadequate glycemic control (A1C 7.5% to 11%) were randomized 2:1 to the addition of either 100 mg of JANUVIA or placebo, administered once daily

It is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist (RA)