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GDH catalyzes the dehydrogenation of glutamate, meanwhile, NAD+ is reduced to NADH, Which under the action of hydrogen transmitter, transfer electrons to WST-8 to produce the yellow product

In addition, other biological responses that decrease the potency of the drug product can occur 37

Gut microbiota and intestinal mucosa are closely combined to form a biological barrier, which controls exogenous pathogenic bacteria and toxins in the intestinal lumen and inhibits their colonization and proliferation (71)

doi: 10.1016/S0021-9258(18)99004-6 120 RushmoreT

The role of IGF/IGF-1R signaling in hepatocellular carcinomas: stemness-related properties and drug resistance