is glutathione carcinogenic A Michael acceptor undergoes conjugate addition, making it carcin Oxidative Stress and its Role

10.1016/j.gim.2024.101138 221 TungC.VarzidehF.FarroniE.MoneP.KansakarU.JankauskasS

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Homma T, Kobayashi S, Sato H, Fujii J (2019) Edaravone, a free radical scavenger, protects against ferroptotic cell death in vitro

Supporting Role: Helps address visible pigmentation at the source while supporting internal photoprotection-related antioxidant defense against UV-induced stress

Combining GPX4 with iron chelators, antioxidants, or free radical scavengers such as Fer-1, Lip-1, vitamin E, or edaravone can further enhance its protective effects, reducing lipid oxidative damage and slowing OA progression (Kagan et al., 2017