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Current data suggest that the oral formulation leads to clinically meaningful weight loss, but on average, it appears less effective than higher doses of high-efficacy injectable GLP-1 therapies, says Jaime Almandoz, MD, medical director of UT Southwestern Medical Centers weight wellness program
High doses may put additional strain on the kidneys, potentially causing adverse effects
Vitamin B12 is also known for boosting metabolism, which can aid in weight loss
Everyone has two copies of the MTHFR gene