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P-rank scores show that SGLT-2 inhibitors were ranked first in reducing CV death (84.8%) (Additional file 1: Table S2)

Applied Microbiology and Biotechnology, 102(23), 1010310117

SCFAs, particularly butyrate, are key metabolites produced through the microbial fermentation of dietary fiber 50 , with their depletion representing a hallmark of obesity-associated dysbiosis 51,52

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6 BiogerontologyStudies on gene-expression and telomere-related effects attributed to Epithalon in model systems

The underlying repair processes, including new blood vessel formation that studies have examined in animal models, are the plausible mechanism, though the human timeline is not precisely established