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2022;6:e21.00156

Protamines: lessons learned from mouse models

Notably, both DFO and ammonium ferric citrate enhance erastin-induced cell death, implying that although systemic iron overload exists in FRDA, cytosolic iron may still be limiting, and iron metabolism is dysregulated, contributing to cellular vulnerability

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GSH is oxidized for the reduction of excess H2O2 in the AsA-GSH cycle (Foyer et al., 1997