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As compared to loop diuretics, SGLT2-i may distinctly regulate the interstitial versus intravascular compartment selectively reducing interstitial oedema, which has been observed in HF and DKD, with minimal change in blood volume

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Wang L, Xu R, Kaelber DC, Berger NA

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