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Using a single-blind trial design, a proof of concept has evaluated the progress of 45 patients with moderate PD, randomly assigned to receive subcutaneous exenatide injections for 12 months or as controls (Aviles-Olmos et al., 2013)

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Funding This work was supported by Fondos Federales HIM 2016/013 SSA 1258

15 Histological features The features are subtle, comprising slight hyperkeratosis, variable acanthosis and elongation of the epidermal ridges, accompanied by increased pigmentation in the basal region (Figs 25.2225.24)

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Assay kits for SOD, CAT, and GSH-PX were all purchased Beyotime Biotechnology Co., Ltd