[9,10,11] Acetaminophen-related liver toxicity is responsible for about half of all cases of acute liver failure in the United States.[12] Acetaminophen toxicity is the #1 reason for liver transplants in the USA, and the #2 reason for liver transplants worldwide.[13] This risk is especially high in people who drink alcohol: Check out my article & video on The Hangover Remedy That Can Kill You. In summary: Paracetamol is mean to the liver, and it doesnt take much more than the recommended dose to cause major harm
doi: 10.1002/ajmg.a.61173 215 StromS
178 ZhengF.YanL.ZhongB.YangZ.XieW
Vendors shipping from China or India may offer lower prices, but the tradeoffs in delivery reliability and product handling during transit are significant
However, sterility of the product matters significantly in this context
Patients in stable remission may be considered differently from those with active inflammation, and specialist assessment is recommended before starting treatment