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Where TH overlapped extensively with the GLP-1Rexpressing neurons in the AP, fluorescently labeled semaglutide was highly abundant

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The authors conclude: In the STEP TEENS trial, treatment with semaglutide 2.4 mg once weekly for 68 weeks was associated with a significant reduction of levels of the liver enzyme alanine aminotransferase compared with placebo. Dr Weghuber adds: Fatty liver disease is the most frequent liver disease in adolescents with no drug therapy currently available

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Tholier, J., Fliss, I., Jean, J