doi: 10.1016/j.tem.2024.05.002 Summary Keywords food preferences, gastrointestinal hormones, glucagon-like peptide 1, gut-brain axis, obesity, taste, taste receptors Citation Doval-Caballero JLE, Ferreira-Hermosillo A, Eugenio-Ponce GD, Garca-Senz MR, Ibarra-Salce R, Tenorio-Rojo AP, Luna-Avila ES, Gete-Palacios PC, Prez-Hernndez F, Rojas-Miln E, Lpez-Cruz LA and Mndez-Hernndez CA (2026) Potential role of glucagon like peptide 1 in taste receptors
Initially, the pathogenesis of NASH was explained by the 2-hit hypothesis, where the first hit, hepatic triglyceride accumulation (steatosis), increases the livers susceptibility to injury from second hits, such as inflammatory cytokines, mitochondrial dysfunction, and oxidative stress [37,38]
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