It has been validated in the population of interest ( The Beck Depression Inventory I (BDI-I) was used to evaluate depression symptoms, which assesses psychic, physical, and cognitive aspects, not including anxiety symptoms (Jurado et al., 1998)
Most human data consist of small case series without control groups, making it difficult to determine whether improvements are due to the peptide, placebo effect, or natural healing
Again, there is minimal research on microdosing, but proponents tout a few potential perks: Milder side effects: Ozempic, Zepbound, and other similar medications can cause gnarly gut issues (nausea, vomiting, diarrhea)
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PLoS ONE 10:e0126978
The safety and efficacy of specific compounded formulations haven't been established through FDA-approved clinical trials
