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The exact amount depends on the patients health, how bad the deficiency is, and how well they respond to treatment

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BMJ 2011;342:d549

Assessing the quality of reports of randomized clinical trials: is blinding necessary

Strength points and limitations Based on our knowledge, this is the most updated meta-analysis on this topic, including all available evidence based on our inclusion criteria of including only controlled studies, either RCTs or controlled observational studies, to reach the highest accessible quality of evidence from the available evidence found in the literature

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