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doi: 10.1016/j.freeradbiomed.2016.08.028

Agarwal, P

Copper is an essential cofactor for mitochondrial complex IV (Cyt C oxidase) and antioxidant enzymes (e.g., SOD1), but excess copper is highly toxic

Other brand-name FDA-approved drugs include Ozempic (semaglutide), Rybelsus (semaglutide pills), and Victoza (liraglutide)

Both medications affect appetite and metabolism through different pathways, but their combined use raises cardiovascular concerns that most evidence-based guidelines do not support

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