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For example, elevated levels of certain saturated fatty acids could indicate a heightened risk of lipotoxicity, which would guide the appropriate use of fatty acid metabolism modulators (138)

United States FDA status: Not approved

doi: 10.1158/0008-5472.CAN-08-0410

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Not all patients with excess fat mass develop T2D (although many have prediabetes) because the level at which adiposopathy is established is variable and based on various factors including central (visceral) vs peripheral (subcutaneous) distribution, sexual dimorphism, adipocyte endowment in childhood, and intrauterine and neonatal epigenetic imprinting as that observed in neonates with low and high birth weight who are both at increased risk of obesity and T2D [14, 15]

This targeted delivery can be particularly beneficial for addressing specific skin concerns, such as wrinkles, hyperpigmentation, or dryness [5]