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Toxicol Appl Pharmacol 203:201218 Winston GW, DiGuilio RT (1991) Prooxidant and antioxidant mechanisms in aquatic organisms

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Histidine 103 in Fra2 is an iron-sulfur cluster ligand in the [2Fe-2S] Fra2-Grx3 complex and is required for in vivo iron signaling in yeast

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While less pronounced than with Hexarelin, they represent a meaningful off-target hormonal perturbation that is absent with ipamorelin

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