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doi: 10.1161/ATVBAHA.119.313286, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 16.Soveyd N, Abdolahi M, Bitarafan S, Tafakhori A, Sarraf P, Togha M, et al
196 In the tumor environment, succinate could be produced and released by tumor cells, and via interacting with succinate receptor 1 to activate phosphoinositide-3-kinase/protein kinase B pathway and upregulate HIF-1, inducing macrophage polarization, and enhancing tumor cell metastasis
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A reverse transcription kit (Vazyme, China) was employed to synthesize cDNA from the extracted RNA
It turns a vague chat about symptoms into a focused, evidence-based discussion, helping you get the support you need sooner