It is however reassuring to me that we have more evidence that oral semaglutide can be effective for weight loss
It describes a scenario where the hormone imbalance causes a relative rise in androgens (male hormones) alongside insulin resistance, which stalls egg development
At 72 weeks, tirzepatide vs semaglutide produced 20.2% mean weight loss versus 13.7% in SURMOUNT-5, the first randomized head-to-head trial between them (NEJM, May 2025)
Flying with GLP-1 medications requires some extra planning, but by following these guidelines, you can ensure a smooth and stress-free journey
Tirzepatide versus dulaglutide Among patients in the expanded population who initiated tirzepatide or dulaglutide, the 1-year risk for the primary endpoint including all-cause mortality in the tirzepatide group was 1.4% (95% CI 1.3% to 1.6%) versus 1.8% (95% CI 1.5% to 2.0%) for dulaglutide
Mounjaro is available as part of our weight loss service