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In this context, the consideration of dose-dependent side effects, such as exacerbating breathing difficulties in obstructive sleep apnea patients, impaired blood glucose control when consumed with carbohydrate-rich meals, and an increased risk of nighttime falls due to drowsiness, especially in the elderly, is imperative [236,237,238]

Focus on lifestyle and nutrition changes If you cant get medication right away, dont underestimate the impact of lifestyle changes

The combination of PBD and an antibody against ApoD demonstrated a senolytic readout by eliminating senescent fibroblasts without any effect on young cells

These findings are supported by in vivo research, such as the study by Muizzuddin et al

May 9 [cited 2024 May 20];20(3)

Body composition changes and deeper metabolic benefits typically develop over 36 months of consistent use