This variability likely stems from tissue-specific differences in iron demand, metabolic activity, regulation, and susceptibility to iron-induced cellular damage that requires further clarification
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Nat Rev Nephrol 12(2):7381 Muskiet MHA, Tonneijck L, Smits MM, Kramer MHH, Heerspink HJL, van Raalte DH (2015) Pleiotropic effects of type 2 diabetes management strategies on renal risk factors
doi: 10.1093/bmb/ldr030 41 FerrariSMRagusaFEliaGPaparoSRMazziVBaldiniEet al