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Keywords: peptide, immune tolerance, lupus, regulatory T cells, immunotherapy, cytokine, chemokine Introduction Autoimmune rheumatic diseases carry a significant burden of morbidity and mortality and have a substantial economic impact on both individuals and the society as a whole

Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution

GLP-1 medications target several of these problems at once

APAP is an oral drug absorbed through the intestine and metabolized by the liver

However, during times of severe physiological stress, viral infection, or chronic inflammation, the body's demand for glutamine drastically outpaces its supply, leading to cellular starvation and the subsequent breakdown of the intestinal barrier

Several specialized targeted nanocarriers, such as liposomes, dendrimers, inorganic nanoparticles and inorganic nanoparticles, have been developed for skin cancer treatment [170]