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That doesn't necessarily mean the first medication "failed." People respond differently to GLP-1 drugs, and some tolerate or respond to one medication better than another
This titration process continues incrementally, with dosages typically escalating to 0.5 mg, then 1 mg, and potentially up to the maximum approved dose of 2 mg per week, based on your individual response, tolerance, and therapeutic goals
Those struggling with obesity or overweight conditions, especially when traditional lifestyle interventions alone havent been effective, may benefit from GLP1 therapy
As such, the AMYR agonists (combined with other incretin class members) could represent the elusive drug candidate to address the multi-hormonal dysregulations of diabetes subtypes and qualify as a precision medicine approach that surpasses the long overdue division into T1DM and T2DM
Med 384 , 11131124 (2021)
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