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S -adenosylmethionine leads to genome-wide alterations in transcription profiles"

ADI-R Reciprocal Social Interaction and/or Total score

This compromised mitochondrial function is driven by the combination of a shortfall in glutathione precursor amino acids (cysteine and glycine) and the accumulation of homocysteine (a toxic transsulfuration/glutathione biosynthesis pathway intermediate) [93]

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2.2 Ferroptosis and its regulatory pathways Ferroptosis, a distinct form of regulated cell death first defined by Dixon et al

The glutathione system of peroxide detoxification is less efficient in neurons than in astroglial cells