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Gastrointestinal side effects were the most frequently reported issue, with 64.4% of patients experiencing nausea and 45.4% reporting vomiting

5.8 Vitamin B12 Deficiency In metformin HCl clinical trials of 29-week duration, a decrease to subnormal levels of previously normal serum vitamin B12 levels was observed in approximately 7% of metformin-treated patients

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Off-label uses include weight loss, management of insulin resistance, and sometimes for conditions like PCOS under medical supervision

Semaglutide and Diverticulitis: Safety Considerations for Patients Taking semaglutide with diverticulitis is not automatically contraindicated, but it requires clear communication between you, your gastroenterologist, and your weight loss provider