Whether affecting skin, liver, lungs, or nervous system tissue, the underlying mechanism involves similar gene expression changes that promote regeneration and reduce damage accumulation
It has been recently shown [60] that T cells from depressed patients displayed a compromised metabolic profile accompanied by heightened gene expression of CTP1a (carnitine palmitoyltransferase 1 A), the mitochondrial enzyme responsible for ACs synthesis
Then, the relationships between DAMs and DEGs were intuitively presented through the correlation network, and the top 10 DEGs by expression level and the top 5 DAMs by relative abundance were selected for plotting, followed by the plotting of KEGG pathways to obtain the pathways simultaneously enriched by the DAMs and DEGs
J Biol Chem 289:72937306 Sheikhbahaei F, Khazaei M, Rabzia A, Mansouri K, Ghanbari A (2016) Protective effects of thymoquinone against methotrexate-induced germ cell apoptosis in male mice
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