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Saxenda may cause gallbladder problems, including gallstones

The Rebound Effect One of the most widely reported outcomes of discontinuing GLP-1 and GIP receptor agonists like tirzepatide is significant weight regain

Companies that outsource analytical comparability work to CDMOs rather than building internal capability are exposed to timeline risks and do not accumulate the expertise needed to execute multiple biosimilar programs efficiently

As well as having no significant effect on weight, being a laxative, psyllium husk may result in side-effects including diarrhoea and flatulence

Other contraindications include a prior serious allergic reaction to semaglutide

The right choice depends on individual eligibility, tolerability, comorbidities, preferences, and accessnot on averages alone