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Results showed significant differences in the blood absorption and pharmacokinetic characteristics of berberine between groups, with differences being largely dependent on variations in gut microbiota, and their corresponding intestinal metabolic capacities

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[6] Dutta S, Majzoub A, Agarwal A

Journal of Cosmetic Dermatology 14(2):83-90. [doi.org]

Knockdown of lactate dehydrogenase by adeno-associated virus-delivered CRISPR/Cas9 system alleviates primary hyperoxaluria type 1