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Global disruption of Gclm results in mice (GCLM knockout) that have 15% of hepatic GSH levels seen in wild-type mice 16

These individuals can be identified by administration of TRH, which will induce an increase in serum T 4 and T 3 if the thyroid has recovered(103)

After he had received the combination of all therapies (TPE, UCT-MSC-EXs, Epitalon, and Semax), the patients CNS-VS testing, performed in December 2023 (18 months after baseline testing), showed significant improvement in composite memory, verbal memory, reaction time, and psychomotor speed, going from 2/12 in the average category at baseline to 7/12 in the average category (Table 4)

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