GLP-1 agonists: Overview, how they work, and more GLP-1s like semaglutide might not have been intended as weight-loss medications, but they are on track to be game changers for treating obesity
However, injectable formulations may provide more consistent potency at currently approved doses
The three eligibility tiers, at a glance The tiers are pathways, not exclusive BMI ranges
Diabet Technol Ther 13:11451154
Semaglutide ODT may be useful for patients who prefer a needle-free option, but it should not be assumed to be identical to injectable semaglutide
Some patients benefit from transitioning to non-pharmacological weight management strategies during the planning phase, while others may need brief insulin therapy or older-generation diabetes medications if blood sugar control remains a concern