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The clinical data confirms this: Very surprisingly, ipamorelin did not release ACTH or cortisol in levels significantly different from those observed following GHRH stimulation. This selectivity makes it the cleanest GHRP available and the ideal complement to Tesamorelins GHRH activity

European archives of psychiatry and clinical neuroscience, 240(4-5), 288-291

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What changes across the cycle is how your body responds, not how often you inject

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