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This discovery underscores the need for further investigation into scavenger receptors (e.g., CD36, SR-BI, SR-BII) for their possible role in heme uptake and detoxification in mammalian species

wherein the average molecular weight of said polymer ranges from about 50,000 to about 10,000,000, as determined by gel permeation chromatography

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It the only FDA-approved peptide for reducing visceral adipose tissue (VAT) in HIV-associated lipodystrophy

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331,332 Currently, a wide range of clinical trials are ongoing in which APR-246 administration has finished or has not yet been completed 12,333,334,335 (Table 3)