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Another proposed mechanism that involves improved glucose uptake is related to the increase in glucose transport proteins (GLUT-2 and GLUT-4) by GLP-1 [51]

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Davies said several GLP-1/glucagon dual agonists have moved on to phase 2 or phase 3 trials, including survodutide (Boehringer Ingelheim), efinopegdutide (Hanmi Pharmaceutical), mazdutide (Eli Lilly and Innovent) and pemvidutide (Altimmune)

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