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To boost GSH levels naturally, consume more sulfur- and selenium-rich foods, increase vitamin C intake, exercise regularly, and get enough sleep

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The review also documented how GCL expression is transcriptionally upregulated by electrophiles through antioxidant response elements (ARE/EpRE) in the GCLC and GCLM promoters establishing the Nrf2/ARE pathway as the master regulator of GSH biosynthetic capacity under stress conditions

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