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According to the American Diabetes Association , its been a first-choice treatment for type 2 diabetes for decades

Studies show that iron accumulation in renal tubular cells is a crucial factor in causing kidney damage, and by intensifying oxidative stress, it further damages the tubular structure, resulting in the ongoing deterioration of renal function [10]

Please see Figure 2 for information on insulin therapy for type 2 diabetes

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Proper sleep hygiene and behavioral therapy are often recommended as first-line approaches