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An open-label, single-arm pilot study involving 21 patients, evaluated the effect of 3,000 mg ALC daily on the intra-epidermal nerve fiber (IENF) density and mitochondrial DNA (mtDNA) copies/cell

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Acta Obstetricia et Gynecologica Scandinavica, 104(2), pp.258266

However, these trials measure surface appearance rather than underlying tissue biology

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