1,4 Painful DN, often associated with SFN, occurs in approximately 25% of diabetes patients and significantly impacts the quality of life due to chronic pain and sensory disturbances
A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight).2, 3, 4, 5, 6, 7 Tirzepatide has been reported to have potential cardiovascular benefits in addition to its glucose-lowering effects

Managing menstrual changes If youre experiencing menstrual changes while taking Mounjaro, these practical strategies may help: For heavier periods: Plan ahead: Keep extra menstrual products available Consider period underwear or menstrual cups as backup protection Stay hydrated to help replace lost fluids Monitor iron intake through diet or supplements if recommended by your healthcare provider Take pain relievers like ibuprofen if approved by your doctor to help with flow and cramping For irregular cycles: Track your periods using an app or calendar to identify patterns Pack menstrual products when travelling or at work in case of unexpected bleeding Consider non-hormonal methods if using contraception, as Mounjaro may affect the absorption of oral contraceptives Contraception considerations Mounjaro can potentially affect the absorption of oral contraceptives by slowing how quickly food moves through your stomach

Healthcare professionals may recommend blood tests to assess electrolyte levels and renal function if symptoms are protracted
Reconstitution errors
Dig Liver Dis 2010;42:320-330