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Selon cette recherche, la mthode de traitement principale est la supplmentation en vitamine B12

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Unlike GLP-1 agonists that reduce appetite or growth hormone peptides that stimulate lipolysis, the compound addresses fat metabolism at the enzymatic level: it removes the molecular governor that locks adipocytes into a low-energy-expenditure state, potentially restoring normal metabolic function in fat tissue where NNMT is overexpressed

Curran JE, Jowett JBM, Elliott KS, Gao Y, Gluschenko K, Wang J et al (2005) Genetic variation in selenoprotein S influences inflammatory response