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A cold compress applied for 10 to 15 minutes within the first hour can limit bruise size

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In particular, a recent work from Dembitskaya et al

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Up-regulation of cyclooxygenase-2 expression and prostaglandin E2 production in human endometriotic cells by macrophage migration inhibitory factor: involvement of novel kinase signaling pathways

I've read potassium can drop but mainly in the loading phase