The STEP UP trial, a Phase 3b study published in The Lancet Diabetes & Endocrinology in 2025, evaluated a 7.2 mg weekly injection dose in over 1,400 adults with obesity (BMI of 30 or higher) and without diabetes
The active ingredient affects the body identically regardless of the source, and the dehydration risk does not change based on whether you are using pharmacy-sourced or compounding pharmacy formulations
33 It is desperately unsettling watching slimfluencers on Tik Tok (who seem to be predominantly women) excitedly starting their new course of Mounjaro, only to experience a new form of agony as they slowly and tearfully realise that there is no destination
However, most of the PK studies demonstrated that the absorption characteristics of the oral drugs were not affected, therefore unsurprisingly, the co-exposure to a GLP1RA did not alter the AUC
So, if thats you, Ozempic isnt the right fit
Overweight is defined as body mass index of 27kg/m2 or greater and has one weight-related problem mentioned above or a BMI of 30 kg/m2 or greater
