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In plants, As alters various metabolic pathways in cells including the interaction of substrates/enzymes with the sulfhydryl groups of proteins and the replacement of phosphate in ATP for energy
What they found: NR is rapidly absorbed orally , peak at 30 minutes NR is converted to NAD+ in multiple tissues , liver, muscle, blood Plasma NAD+ rises 2 to 8 after a single dose Optimal dosing regimens: 100 to 1000 mg No accumulation of toxic metabolites Why it matters: This is the reference pharmacokinetic publication for NR and NMN
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