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It has been shown that L-glutamine stimulates GLP-1 secretion by activating Gs through Gs-coupled receptors like taste receptor type 1 member 3 (TAS1R3) in intestinal L-cells 28

10.1002/mnfr.201800147 72 ZhangM.LiX.XiangC.QinY.HeJ.LiB

Moreover, the surface modification of the NPs with targeting ligands can further improve the specificity and efficacy of BDNF delivery, which promotes the survival and function of the neurons (183)

Glucose / IGF-1: Higher GH output can affect insulin sensitivity

doi:10.1016/S0140-6736(23)01053-X Abdrabou Abouelmagd A, Abdelrehim AM, Bashir MN, et al

Semaglutide: Well-characterized GI side effects (nausea 44%, diarrhea 30%, vomiting 24%)